• 中国科技论文统计源期刊(中国科技核心期刊)
  • 中国医药卫生核心期刊
  • 中国抗癌协会系列期刊

颈动脉粥样硬化斑块分布特点的Meta分析

唐琪, 夏依达·吐尔逊, 穆玉明

唐琪, 夏依达·吐尔逊, 穆玉明. 颈动脉粥样硬化斑块分布特点的Meta分析[J]. 循证医学, 2013, 13(2): 116-119. DOI: 10.3969/j.issn.1671-5144.2013.02.012
引用本文: 唐琪, 夏依达·吐尔逊, 穆玉明. 颈动脉粥样硬化斑块分布特点的Meta分析[J]. 循证医学, 2013, 13(2): 116-119. DOI: 10.3969/j.issn.1671-5144.2013.02.012
TANG Qi, XIA Yi-da·TU Er-xun, MU Yu-ming. A Meta-analysis of Distribution of Carotid Artery Atherosclerotic Plaques in Patients with Atherosclerotic[J]. Journal of Evidence-Based Medicine, 2013, 13(2): 116-119. DOI: 10.3969/j.issn.1671-5144.2013.02.012
Citation: TANG Qi, XIA Yi-da·TU Er-xun, MU Yu-ming. A Meta-analysis of Distribution of Carotid Artery Atherosclerotic Plaques in Patients with Atherosclerotic[J]. Journal of Evidence-Based Medicine, 2013, 13(2): 116-119. DOI: 10.3969/j.issn.1671-5144.2013.02.012

颈动脉粥样硬化斑块分布特点的Meta分析

基金项目: 新疆医科大学第一附属医院循证医学专项基金资助项目(2010XZ01)
详细信息
    作者简介:

    唐琪(1976-),男,湖南永州人,医学学士,从事心血管超声研究。

    通讯作者:

    穆玉明,Tel: 0991-4366187, E-mail: mym1234@126.com

  • 中图分类号: R540.4

A Meta-analysis of Distribution of Carotid Artery Atherosclerotic Plaques in Patients with Atherosclerotic

  • 摘要: 目的 系统评价颈总动脉斑块分布特点对颈动脉粥样硬化的影响。 方法 按Cochrane 系统评价方法,计算机检索Cochrane图书馆、CENTRAL、MEDLINE、EMBASE、SCI、CBM、CNKI等数据库,并手工检索相关会议文献及已发表与未发表的资料。检索语言为中英文。按照纳入标准严格筛选文献,并进行文献方法学质量评价,对可以合并分析的数据采用Cochrane协作网提供的RevMan 5.1软件进行Meta分析。 结果 经过全面检索及筛查后,共纳入5个随机对照研究。Meta分析结果显示: 颈总动脉斑块左右侧分布率差异有统计学意义,左侧多于右侧,比值比0.72,95%可信区间 0.67~0.78,P<0.000 01。 结论 颈总动脉斑块的形成表现为左侧多于右侧,并且左侧更能提示颈动脉粥样硬化的程度;因本系统评价仍有一些未纳入的评价指标,上述结论需更多设计严谨的随机对照试验加以验证。
    Abstract: Objective To assess distributions of carotid plaque in patients with atherosclerosis in the carotid arteries. Methods We electronically searched the Cochrane Library, CENTRAL, MEDLINE, EMBASE, SCI, CBM and CNKI databases; we also hand-searched some published and unpublished references and meeting papers. Languages were restricted to Chinese and English. We strictly adopted references according to inclusion criteria. The studies were evaluated by literature methodology. The Cochrane Collaboration’s RevMan 5.1 software was used for meta analysis. Results We identified 5 randomized control trials after comprehensively searching and selecting. The results showed statistically significant differences in carotid plaque distributions, and the incidence of those with plaque in the left side was higher than the right side, OR=0.72, 95%CI (0.67, 0.78), P<0.000 01. Conclusions Compared with the right side, the plaque formation in the left side of common carotid artery were more frequency, while the distribution of left side might be indicated the degree of atherosclerosis than the right side. There were some criteria not included in this systematic evaluation, and thus more high quality RCT should be recruited and assessed in future study.
  • [1] RS, Arts T, Hoeks AP. Wall shear stress—An important determinant of endothelial cell function and struncture—in the arterial systerm in vivo. Discrepancies with theory[J]. J Vasc Res, 2006,43(3): 251-269.
    [2] A, Irace C, Carallo C, et al. In vivo association between low wall shear stress and plaque in subjects with asymmetrical carotid atherosclerosis[J]. Stroke, 1997,28(5): 993-998.
    [3] 张祖德, 周青, 等. 舒降之对颈动脉粥样硬化影响的超声评价[J]. 中国超声医学杂志, 2003,19(2): 89-90.
    [4] 刘关键. 隐蔽分组(分配隐藏)和盲法的概念、实施与报告[J]. 中国循证医学杂志, 2007,7(3): 222-225.
    [5] 颈动脉粥样硬化斑块生长部为与血管内膜及血流动力学的相关性研究[J]. 中国超声医学杂志, 2012,28(4): 334-337.
    [6] 颈动脉彩色多普勒超声在预防脑梗死中的应用价值[J]. 齐齐哈尔医学院学报, 2011,32(10): 1567-1568.
    [7] 彩色多普勒超声对颈动脉粥样硬化的诊断价值[J]. 放射学实践, 2006,21(8): 852-854.
    [8] 颈动脉斑块与缺血性脑血管病的相关性[J]. 临床医学, 2010,30(10): 92-93.
    [9] S, Hallerstam S, Jensen-Urstad K, et al. Relationship between intima-media thickness in the common carotid artery and atherosclerosis in the carotid bifurcation[J]. Stroke, 1998,29(7): 1378-1382.
    [10] 颈部动脉粥样硬化的彩超探查及其与脑梗塞的相关性的探讨[J]. 中国超声医学杂志, 2004, 20(2): 146-147.
    [11] AF, Wulu JT Jr, Crotty B. Carotid plaque ultrasonic heterogeneity and severity of stenosis[J]. Stroke, 2002,33(7): 1772-1775.
    [12] A, Svindland A, Lindboe CF. Pathogenesis of carotid thrombosis[J]. Stroke, 1989, 20(11): 1477-1483.
    [13] 脑梗死与颈动脉粥样硬化斑块的相关性分析[J]. 中国动脉硬化杂志, 2009, 17(12): 1030-1032.
    [14] 陈庆伟, 王志刚, 等. 颈动脉粥样硬化超声与血管造影的对比研究[J]. 中华超声影像学杂志, 2007,16(4): 306-309.
    [15] 颈动脉粥样硬化斑块与相关因素的探讨[J]. 临床超声医学杂志, 2009,11(1): 34-36.
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出版历程
  • 收稿日期:  2012-05-02
  • 发布日期:  2013-04-27

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