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    卢杨, 屈会起. 中国心肌梗死患者血管紧张素Ⅰ转换酶基因插入/缺失多态性Meta分析[J]. 循证医学, 2001, 1(1): 18-21. DOI: 10.3969/j.issn.1671-5144.2001.01.005
    引用本文: 卢杨, 屈会起. 中国心肌梗死患者血管紧张素Ⅰ转换酶基因插入/缺失多态性Meta分析[J]. 循证医学, 2001, 1(1): 18-21. DOI: 10.3969/j.issn.1671-5144.2001.01.005
    shu
    Meta-analysis on the association of the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and myocardial infarction in Chinese population[J]. Journal of Evidence-Based Medicine, 2001, 1(1): 18-21. DOI: 10.3969/j.issn.1671-5144.2001.01.005
    Citation: Meta-analysis on the association of the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and myocardial infarction in Chinese population[J]. Journal of Evidence-Based Medicine, 2001, 1(1): 18-21. DOI: 10.3969/j.issn.1671-5144.2001.01.005
    shu

    中国心肌梗死患者血管紧张素Ⅰ转换酶基因插入/缺失多态性Meta分析

    Meta-analysis on the association of the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and myocardial infarction in Chinese population

      摘要
    • 摘要: 目的对中国人血管紧张素Ⅰ转换酶(ACE)基因内含子16插入(I)/缺失(D)多态性与心肌梗死的关联性进行Meta分析.方法以心肌梗死组和健康对照组基因型分布的比值比(OR)为统计量.全面检索到相关文献,剔除不符合要求的文献,排除发表偏倚的影响,应用REVMAN3.1软件对各研究结果进行一致性检验和采用相应的数学模型进行数据合并.结果相关文献未发现显著发表偏倚,数据合并结果心肌梗死组和健康对照组DD/(ID+II)OR 2.33,95%可信区间(CI)1.65～3.29,(P＜0.01),II/(ID+DD

       

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