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    刘媛, 余细勇, 单志新, 林秋雄, 杨敏, 郑猛. 随机、开放法评价卡维地洛对扩张型心肌病心衰患者血浆M30抗原水平影响的临床研究[J]. 循证医学, 2003, 3(4): 211-214. DOI: 10.3969/j.issn.1671-5144.2003.04.005
    引用本文: 刘媛, 余细勇, 单志新, 林秋雄, 杨敏, 郑猛. 随机、开放法评价卡维地洛对扩张型心肌病心衰患者血浆M30抗原水平影响的临床研究[J]. 循证医学, 2003, 3(4): 211-214. DOI: 10.3969/j.issn.1671-5144.2003.04.005
    shu
    Effects of carvedilol on plasma M30 neo-epitope in patients with congestive heart failure secondary to dilated cardiomyopathy——an open and randomized clinical study[J]. Journal of Evidence-Based Medicine, 2003, 3(4): 211-214. DOI: 10.3969/j.issn.1671-5144.2003.04.005
    Citation: Effects of carvedilol on plasma M30 neo-epitope in patients with congestive heart failure secondary to dilated cardiomyopathy——an open and randomized clinical study[J]. Journal of Evidence-Based Medicine, 2003, 3(4): 211-214. DOI: 10.3969/j.issn.1671-5144.2003.04.005
    shu

    随机、开放法评价卡维地洛对扩张型心肌病心衰患者血浆M30抗原水平影响的临床研究

    Effects of carvedilol on plasma M30 neo-epitope in patients with congestive heart failure secondary to dilated cardiomyopathy——an open and randomized clinical study

      摘要
    • 摘要: 目的测定扩张型心肌病(DCM)心衰患者血浆中细胞凋亡产物M30抗原水平以及卡维地洛对其的影响.方法39例DCM心衰患者,随机分为常规治疗组和卡维地洛治疗组,予以药物干预8周,检测治疗前后血浆M30水平变化,正常对照组25例,同时检测血浆M30水平.结果DCM心衰组血浆M30抗原水平与正常对照组相比明显升高(P＜0.01).重度心衰心功能Ⅳ级患者血浆M30抗原水平较心功能Ⅱ级患者明显升高(P＜0.01).心衰患者中卡维地洛组治疗后血浆M30水平明显低于治疗前(P＜0.05),而常规治疗组治疗前后无显著性差异

       

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