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    林旭滨, 蔡清清, 史艳侠, 李宇红, 周中梅, 郭颖, 韩福才, 谭煌英, 应江山, 印季良, 许立功, 李佩文, 何友兼, 姜文奇, 黄慧强, 管忠震. 冻干人胎盘因子对肿瘤化疗患者免疫功能影响的Ⅱ期临床研究[J]. 循证医学, 2007, 7(2): 80-83. DOI: 10.3969/j.issn.1671-5144.2007.02.006
    引用本文: 林旭滨, 蔡清清, 史艳侠, 李宇红, 周中梅, 郭颖, 韩福才, 谭煌英, 应江山, 印季良, 许立功, 李佩文, 何友兼, 姜文奇, 黄慧强, 管忠震. 冻干人胎盘因子对肿瘤化疗患者免疫功能影响的Ⅱ期临床研究[J]. 循证医学, 2007, 7(2): 80-83. DOI: 10.3969/j.issn.1671-5144.2007.02.006
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    LIN Xu-bin, CAI Qing-qing, SHI Yan-xia, LI Yu-hong, ZHOU Zhong-mei, GUO Ying, HAN Fu-cai, TAN Huan-ying, YING Jiang-shan, YIN Ji-liang, XU Li-gong, LI Pei-wen, HE You-jian, JIANG Wen-qi, HUANG Hui-qiang, GUAN Zhong-zhen. The Impact of Placenta Factor on Immune Function,Quality of Life for Patients with Solid Tumors Treated by Chemotherapy——A preliminary outcome of multicenter,prospective randomized controlled study[J]. Journal of Evidence-Based Medicine, 2007, 7(2): 80-83. DOI: 10.3969/j.issn.1671-5144.2007.02.006
    Citation: LIN Xu-bin, CAI Qing-qing, SHI Yan-xia, LI Yu-hong, ZHOU Zhong-mei, GUO Ying, HAN Fu-cai, TAN Huan-ying, YING Jiang-shan, YIN Ji-liang, XU Li-gong, LI Pei-wen, HE You-jian, JIANG Wen-qi, HUANG Hui-qiang, GUAN Zhong-zhen. The Impact of Placenta Factor on Immune Function,Quality of Life for Patients with Solid Tumors Treated by Chemotherapy——A preliminary outcome of multicenter,prospective randomized controlled study[J]. Journal of Evidence-Based Medicine, 2007, 7(2): 80-83. DOI: 10.3969/j.issn.1671-5144.2007.02.006
    shu

    冻干人胎盘因子对肿瘤化疗患者免疫功能影响的Ⅱ期临床研究

    The Impact of Placenta Factor on Immune Function,Quality of Life for Patients with Solid Tumors Treated by Chemotherapy——A preliminary outcome of multicenter,prospective randomized controlled study

      摘要
    • 摘要: 目的 探讨冻干人胎盘因子(PF)对肿瘤化疗患者免疫功能、生活质量、不良反应和客观疗效的影响.方法 收治116例患者,随机分为试验组(A组,化疗+PF组)及对照组(B组,单用化疗组),化疗至少2个疗程.试验组第1日开始用胎盘因子,隔日一次,每次18 mg肌注,持续3～4周.结果 在免疫指标方面,除CD8外,治疗组CD3、CD4、CD4/CD8比值和NK细胞活性水平均有不同程度的升高,对照组则有不同程度的下降(均为P=O.000).PF使纯蛋白衍生物皮试阳性率和强阳性比例明显增高(P=0.008).治疗组腹泻 ......

       

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