Multislice Computed Tomography and Echocardiography in the Diagnosis of Congenital Heart Disease in Chinese Population: A Meta-Analysis

Objective To perform a meta-analysis to evaluate multislice computed tomography （MSCT） and echocardiography （ECG） in the diagnosis of congenital heart disease in Chinese population. Methods Literature search and review were done. The characteristics of the included articles were appraised and extracted. The pooled weighted sensitivity and specificity for MSCT and ECG were calculated respectively. SROC curves of the two imaging methods were performed and two areas under the curves （AUC） were calculated and compared. Result 9 of 181 retrieved articles fulfilled the inclusion criteria, with a total of 1 303 cardiac deformities. Totally and in detecting extracardiac anomalies, the pooled weighted sensitivities and specificities for MSCT were higher than that for ECG （Ρ<0.01）. The AUC of SROC for MSCT was larger. In intracardiac deformities, the pooled weighted sensitivities for ECG were higher than that for MSCT （Ρ<0.01）. The AUC of SROC for ECG was larger. Conclusions MSCT is superior to ECG in the diagnosis of congenital heart disease in Chinese population, especially in detecting extracardiac anomalies, while ECG has a high diagnostic value in intracardiac deformities.