Meta-Analysis of Ordinal Data and Its Solution by SAS

Objective To introduce methodology for undertaking a meta-analysis on ordinal data and its realization in SAS. Methods It was illustrated on an example data by using two-step method. In the first step, it was calculated treatment effect and its standard error for an individual study by using PROC GENMOD in SAS based on cumulative odds models; in the second step, a classical meta-analysis was proposed for fixed and random effect model by using PROC MIXED in SAS. Results Results from the traditional meta-analysis of summary odds ratio and its 95%CI were same 2.853 9（2.106 4,3.864 8） for fixed and random effect model. Conclusions The procedure SAS PROC GENMOD and MIXED were utilized to undertake a meta-analysis on ordinal data.