Abstract: Objective To investigate the influencing factors of clinical prognosis in patients with papillary urothelial neoplasm of low malignant potential （PUNLMP） after transurethral resection of bladder tumor （TURBT）. Methods Clinical data of 170 patients with low malignant potential bladder PUN after TURBT were retrospectively chosen from January 2013 to December 2019 in The First Hospital of Handan City. Univariate and multivariate methods were used to evaluate the influencing factors of clinical prognosis after TURBT. Results The patients were followed up for 6.5 to 92.0 months with a median time of 27.0 months and no tumor-related death occurred. 42 patients had tumor recurrence, the recurrence time was 2.5~87.5 months, and the median recurrence time was 24.0 months. 24 cases with progression, with the median progression time of 23.5 months ranging from 3.0 to 58.0 months. Univariate analysis showed that the maximum diameter and number of primary tumors were related to the recurrence and progression after TURBT. Multivariate analysis showed that the number of primary tumors was the independent factor affecting the recurrence and progression of bladder PUN patients with low malignant potential after TURBT （P<0.05）. Conclusions The number of primary tumors is closely related to the clinical prognosis of bladder PUN patients with low malignant potential after TURBT and postoperative intravesical chemotherapy should not improve the clinical prognosis of patients.