Abstract: Objective To investigate the relationship between the degree of insomnia and clinical features in patients with depression. Methods Statistical the distribution of gender, age, number of onset and course of disease in patients with insomnia in mild, moderate and severe groups. The total score and each factor score of HAMD-24 were used to evaluate the severity of the disease and to compare the difference of the severity among the mild, moderate and severe insomnia groups. Results The degree of insomnia in patients with depression was significantly different in sex（χ²=7.30,P<0.05）, age of onset（χ²=15.75,P<0.05） and severity of illness （W=42.06, P<0.05）. Among them, patients with depression mainly suffered from mild and moderate insomnia. There were 21 mild insomniacs and 21 moderate insomniacs, accounting for 36.8%, respectively, while there were 15 severe insomniacs, accounting for 26.4%. Female mainly had mild insomnia, while male had moderate insomnia. The more severe the insomnia degree was, the later the onset age started and the more serious the disease was. But there was no statistical difference between the number of onsets（χ²=3.46,P>0.05） and the course of disease （χ²=2.58, P>0.05）. Conclusions Patients with depression mainly suffered from mild and moderate insomnia and female mainly had mild insomnia, while male had moderate insomnia. The more severe the insomnia degree was, the later the onset age started and the more serious the disease was.