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地氟烷和七氟烷用于儿科麻醉术后恢复的Meta分析

刘华, 阮林, 刘叶

刘华, 阮林, 刘叶. 地氟烷和七氟烷用于儿科麻醉术后恢复的Meta分析[J]. 循证医学, 2013, 13(3): 166-172. DOI: 10.3969/j.issn.1671-5144.2013.03.012
引用本文: 刘华, 阮林, 刘叶. 地氟烷和七氟烷用于儿科麻醉术后恢复的Meta分析[J]. 循证医学, 2013, 13(3): 166-172. DOI: 10.3969/j.issn.1671-5144.2013.03.012
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LIU Hua, RUAN Lin, LIU Ye. Desflurane versus Sevoflurane in Pediatric Anesthesia: A Meta Analysis[J]. Journal of Evidence-Based Medicine, 2013, 13(3): 166-172. DOI: 10.3969/j.issn.1671-5144.2013.03.012
Citation: LIU Hua, RUAN Lin, LIU Ye. Desflurane versus Sevoflurane in Pediatric Anesthesia: A Meta Analysis[J]. Journal of Evidence-Based Medicine, 2013, 13(3): 166-172. DOI: 10.3969/j.issn.1671-5144.2013.03.012
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地氟烷和七氟烷用于儿科麻醉术后恢复的Meta分析

  • 广西医科大学附属肿瘤医院麻醉科, 南宁530021

基金项目: 广西自然科学基金资助项目（桂科自0728200）
详细信息
    作者简介:

    刘华（1982-）,女,河南商丘人,在读硕士研究生,研究方向为吸入麻醉。

    通讯作者:

    阮林, Tel: 0771-5333550, E-mail: 1535943930@qq.com

  • 中图分类号: R614

Desflurane versus Sevoflurane in Pediatric Anesthesia: A Meta Analysis

  • Department of Anesthesiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China

摘要

    摘要
  • 摘要: 目的 评价地氟烷和七氟烷用于儿科麻醉术后恢复的效果及不良反应。 方法 电子检索PubMed、Cochrane图书馆、EMBASE、中国生物医学文献数据库（CBM）和维普中文期刊数据库（VIP）,文献检索时间均从建库至2012年2月,收集地氟烷和七氟烷用于儿科麻醉的随机对照试验。按Cochrane Handbook 5.0.1提供的随机对照试验质量评价标准评价纳入研究的方法学质量,使用RevMan 5.0对收集的患者资料进行Meta分析。 结果 纳入9篇随机对照试验,包括840例患儿,其中地氟烷组414例,七氟烷组426例。Meta分析结果显示: 在早期苏醒时间上地氟烷组快于七氟烷组,在术后恢复时间上两组差异没有统计学意义,术后躁动的发生率地氟烷组高于七氟烷组,术后恶心呕吐、严重疼痛和眼心反射两组差异没有统计学意义。 结论 本研究结果表明地氟烷麻醉术后早期苏醒快于七氟烷,术后躁动的发生率高于七氟烷,但在术后恢复、恶心呕吐、严重疼痛和眼心反射方面没有差异。
    Abstract: Objective To evaluate the efficacy and adverse reactions of Desflurane versus Sevoflurane in pediatric anesthesia recovery. Methods We searched PubMed, the Cochrane Library, EMBASE, Chinese Biomedical Database （from establishment to February 2012） for randomized controlled trials （RCTs） about the efficacy and adverse reactions of Desflurane versus Sevoflurane in pediatric anesthesia recovery. Meta-analysis was conducted by RevMan 5.0 software. Result Nine RCTs involving 840 patients were included. The result showed that the early recovery time was shorter in group of Desflurane. There were no significant differences in the postoperative recovery time, postoperative agitation and vomiting （PONV）, severe pain and oculocardiac reflect （OCR） between two groups. Conclusion The limited current evidence shows that the effect of Desflurane is faster than Sevoflurane in early recovery time. The incidence of PONV of Desflurane is higher than Sevoflurane.
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    • 参考文献(17)
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出版历程
  • 收稿日期:  2012-06-23
  • 发布日期:  2013-06-27

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